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Devemos destacar tamb m o que entendemos por Intelectuais
2019-04-22
Devemos destacar também o que entendemos por Intelectuais, ten-do como suporte para A 779 construção do conceito os autores Carlos Altamirano e Jean-François Sirinelli. O termo intelectual, de acordo com Sirinelli, traz em si duas acepções de natureza sociocultural, sendo uma mais ampla, marcada pel
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Splicing machinery dysfunctions have been associated
2019-04-22
Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mutat
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The imbalances in the current R D
2019-04-22
The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle
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Because of the high amplitude
2019-04-22
Because of the high amplitude of atrial signals, atrial sensitivity was decreased from 0.5mV to 0.7mV to 1.0mV. As the sensitivity decreased, atrial sensing was restored gradually. With the sensitivity of 1.0mV, normal atrial sensing with mode switching was restored completely. The sensitivity was p
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br Conflict of interest br Introduction Gastric
2019-04-20
Conflict of interest Introduction Gastric cancer is a major cause of cancer deaths worldwide, particularly in East Asia. Metastatic gastric cancer is associated with poor outcomes. The median overall survival of metastatic gastric cancer ranges from 9 to 13 months despite treated with systemic
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br In this issue of
2019-04-20
In this issue of , Tiffany Chao and colleagues present a systematic, comprehensive, and critical assessment of published estimates of the cost-effectiveness of essential surgery, and thus make an important contribution to the published work on the economics of global health interventions. Their he
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En toda su trayectoria una
2019-04-20
En toda su trayectoria una constante que ha sido reconocida por la comunidad académica y por él mismo, en diversas ocasiones, fue la de “bautizar los nuevos animales”, la de crear conceptos para fenómenos nuevos que consideró específicos, en el marco de la búsqueda en su última etapa de una teoría d
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La relaci n entre el narcotr fico y los
2019-04-20
La relación entre el narcotráfico y los grupos guerrilleros y los paramilitares se ha dado: “[…] no sólo como fuente de financiación sino como actor con intereses propios, ya que han aumentado significativamente las ‘familias’ que se dedican al tráfico de drogas, que a su vez están aumentando sus fo
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Rabies has no cure and by the
2019-04-20
Rabies has no cure, and by the time of clinical onset it is invariably fatal. More than 95% of deaths occur in Africa and Asia, 80% of which are in people living in rural, underserved populations, most of whom are children. Community awareness about the power of preventing dog bites and of life-savi
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To verify this hypothesis OGD was adopted to
2019-04-20
To verify this hypothesis, OGD was adopted to mimic cerebral ischemic injury in rat cortical astrocyte-neuron co-cultures in the present study. This co-cultures system allows us to manipulate astrocytes and neurons respectively, and simultaneously allows the two kinds of cells to exchange soluble me
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order BYL-719 br LEGADO FUJIMORISTA No seu segundo mandato G
2019-04-19
LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias
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Ultraviolet radiation UVR can stimulate melanin
2019-04-19
Ultraviolet radiation (UVR) can stimulate melanin production in human epidermal melanocytes. It is reported that the MC1R-cAMP pathway plays an important role in UVR-induced tanning [22]. Similar to the UVR-induced effect, p38 MAPK signaling is involved in stress-induced melanogenesis. A previous st
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One day after implantation diaphragmatic stimulation was obs
2019-04-19
One day after implantation, diaphragmatic stimulation was observed when the patient was in the seated position, and it could not be resolved by reprogramming the device. We decided to replace the LV lead; however, there were no other vein branches suitable for CRT in the lateral region of the LV (Fi
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MCL has a poor long term response to
2019-04-19
MCL has a poor long-term response to current treatment strategies, for the most commonly used R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone), the remission rate is good (75–96%) but brief in duration. Despite the study of several other chemotherapy regimens
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A recent meta analysis has shown that an enlarged LA
2019-04-19
A recent meta-analysis has shown that an enlarged LA increases the risk of AF recurrence after a single CPVI, regardless of the follow-up duration [5]. This finding can be applied to paroxysmal and persistent AF [6,7]. In clinical practice, measurement of LAD can provide a window into the status of
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