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Acute kidney injury is a
2019-05-07
Acute kidney injury is a common disorder worldwide, occurring in more than 13 million people every year, 85% of whom live in low-income or middle-income countries (LMICs). The disease imposes a severe burden of morbidity and mortality, with a major economic effect on health-care expenditure worldwid
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Programmed death ligand PD L
2019-05-07
Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed
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br Authors disclosure Mark Clemons received honoraria for ta
2019-05-07
Authors\' disclosure Mark Clemons received honoraria for talks from Novartis and Amgen, research funding from Novartis. Case In September 2007 a 9½-year-old boy was diagnosed with a Ewing sarcoma (EWS-FL1 translocation positive) of the right scapula. MRI showed a tumor of 8.0×2.9 ×6.2cm locat
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In addition to CAF in
2019-05-07
In addition to CAF in the primary tumour microenvironment, it is tempting to speculate that fibroblasts within the bone itself may play a role in the establishment of metastatic deposits. Fibroblasts form a major component of the bone marrow stroma and regulate haematopoiesis by secreting a range of
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br Ya desde el siglo xvi
2019-05-06
Ya desde el siglo xvi, Salinas parece aceptar las innovaciones de Ramos Pareja que avanzaban en el siglo xv sobre lo que sería el temperamento igual. La obra de Salinas, Siete libros sobre la música, de 1577, entabla una explícita afinidad con las teorías de su contemporáneo Zarlino, como éste BYL
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Vaccinated individuals might represent a safer source of
2019-05-06
Vaccinated individuals might represent a safer source of hyperimmune serum. Two vaccine candidates will be tested soon in west Africa. If serum from vaccinated individuals has neutralising activity against the virus in cell models, this serum could be used as adjuvant therapy for EVD. In parallel, a
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Para finalizar focaliza se o hospital
2019-05-06
Para finalizar focaliza-se o hospital, lócus de embate desta pesquisa, e recorre-se aos direcionamentos de Donadone, em estudo envolvendo consultores e gerentes no país. Afirma o autor que “[…] é possível visualizar um processo de guerra cultural onde purchase GSK-3 Inhibitor IX visão financeira da
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Christina Dupl a tambi n
2019-05-06
Christina Dupláa también procura en su estudio dar una definición del testimonio, aunque, como sucede con los críticos mencionados hasta el momento, sólo considera el testimonio mediato, dejando IWR-1-endo un lado otras producciones: “El testimonio o discurso-testimonio es un mensaje, la mayoría de
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br Conclusions br Financial support br Conflict of
2019-05-06
Conclusions Financial support Conflict of interest Acknowledgment Introduction Cardiac resynchronization therapy (CRT) has been demonstrated to improve symptoms, quality of life, functional status, and reduce mortality and citco failure-related hospitalizations in patients with New Y
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br Case report A year old man with no known
2019-05-06
Case report A 50-year-old man with no known systemic diseases presented to our facility with a growing huge mass at his left flank and numbness of the left leg. Five years earlier, there was only a small lump over his left flank. However, the soft tissue lesion gradually enlarged, accompanied by
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s6 kinase br Conclusion br Conflict of interest This work
2019-05-06
Conclusion Conflict of interest This work was supported by Medtronic Japan. MN received honoraria from Medtronic Japan, St. Jude Medical Japan and Boston Scientific Japan. YE and TI received honoraria from Medtronic Japan. HS received honoraria from Japan Lifeline. YA, TT, and KK are employees
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br Discussion T wave oversensing is caused by
2019-05-06
Discussion T-wave oversensing is caused by alternations or variations in intracardiac electrograms for reasons such as hyperglycemia, drugs, sympathetic tones, ventricular pacing, and hyperkalemia. Several similar cases of hyperkalemia-induced T-wave oversensing with inappropriate ICD therapies h
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It is noted that in this study BrS patients had
2019-05-06
It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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En otros casos como en de scar
2019-05-06
En otros casos, como en de Óscar de Pablo (1979), predomina el referente histórico como una integrin inhibitors para desarrollar tramas narrativas muy complejas, donde puede mezclarse poesía y reflexión social; en “Nadie (que yo conozca) es Tolomeo III”, aprovecha la imagen de un faraón egipcio de
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Although the long term stability
2019-05-06
Although the long-term stability of childhood intelligence during the life course has been shown in longitudinal studies, studies of the long-term effects of breastfeeding are important. With age, the effects of early developmental factors might either be diluted, because of the effects of later env
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